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KMID : 0378019860290100101
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New Medical Journal
1986 Volume.29 No. 10 p.101 ~ p.103
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Effect of Flubendazole against Ascaris lumbricoides, Trichocephalus
trichiurus and Enterobius vermicularis in infected children
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Abstract
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Effectiveness of flubendazole, a newly introduced as an anthelmintic in Korea, was 8.5 in 28 ascariasis, 28 whipworm infections and 17 pinworm infections among primary school children. All patients were orally given Rubendazole 500mg once. Stools for roundworm and whipworm and specimen for pinworm were examined both before and 25 days after treatment.
After flubendazole treatment all ascariasis and pinworm infected cases were completely cured. On the other hand, in whipworm infections, the cure rate was 82.1%(23 cured among 28 infections), and the egg reduction rate was 67.1%, respectively. Headache(one case), dizziness(2 cases) and abdominal pain(3 cases) were notice as untoward side effects, but they were mild and disappeared within 24 hours. These results demonstrate the excellent effectiveness of flubendazole in treating these helminth infections.
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